Summary of "Sirius"

Fifty years ago, the philosopher Olaf Stapledon published a novel, Sirius, which explores some of the depths of loneliness and alienation to which genetic engineering might lead. Stapledon knew nothing of DNA and molecular biology, but he foresaw the possibility of genetic engineering and saw that it would give rise to severe dilemmas. His hero, Sirius, is a dog endowed with a brain of human capacity by doses of nerve-growth hormone given to him in utero. His creator raised him as a member of...

 Using City Sewage to Survey a City's Microbiome

The team gathered samples over the course of a year from sewage treatment plants in 71 different cities in 31 states, chosen for their geographic spread and range of obesity rates. The leanest city sampled was Steamboat Springs, Colorado, with an obesity rate of 13.5 percent, while the heaviest was St. Joseph, Missouri, with a rate of 37.4 percent. Bacteria from human waste make up just a small proportion of the bacteria found in sewage. But using DNA sequencing, the researchers could identi...

 The DNA Prism

The standard DNA 'prism' is a gel electrophoresis column, that is, a long tube filled with jelly through which an electric current is passed. A solution containing the scissored stretches of DNA, all jumbled together, is poured into one end of the tube. The DNA fragments are all electrically attracted to the negative end of the column, which is at the other end of the tube, and they move steadily through the jelly. But they don't all move at the same rate. Like light of low vibration frequenc...

 Science Unifiers

Now it is generally true that the very greatest scientists in each discipline are unifiers. This is especially true in physics. Newton and Einstein were supreme as unifiers. The great triumphs of physics have been triumphs of unification. We almost take it for granted that the road of progress in physics will be a wider and wider unification bringing more and more phenomena within the scope of a few fundamental principles. Einstein was so confident of the correctness of this road of unificati...